Abstract

A series of N-l,N′-(n + 2)-bis[3-cyano(ethoxycarbonyl)-4,5-dimethylthiophen-2-yl]alkanediamides have been synthesized by acylating 4,5-dimethyl-2-amino-3-cyano(ethoxycarbonyl)thiophenes with the corresponding dicarboxylic acid dichloroanhydrides. The results of biological tests show that the obtained bisamides possess antiinflammatory and analgesic (non-narcotic) activity.

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