Abstract
On the basis of our previous work, in order to seeking for novel compounds with bioactivities to settle for the resistance problem, two series of novel pyrazole oxime ether derivatives have been designed and synthesized containing chlorothiazole group and pyrimidine rings applying the bioisosterism. Their structures were determined by H NMR, IR, elemental analysis and MS, and their bioactivities were performed. Nearly half of the target compounds of series A with chlorothiazole group exhibited good insecticidal activity against culex pipiens pallens (100%, 5 mg•L), several compounds of series A showed good activity against Aphis laburni Kaltenbach (100%, 200 mg/L) and Tetranychus cinnabarinus (100%, 200 mg/L), and the compounds of series B with pyrimidine rings exhibited certain fungicidal activity.
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