Sustainable Valorization of Bio-Valuable Compounds From Pinus By-Products: From Green Extraction Process to Potential Industrial Applications.

Valorizing natural resources through sustainable and eco-friendly processes is a cornerstone in pursuing a greener and more sustainable future. This study focuses on the green extraction of valuable compounds from rubber seed trees (Hevea brasiliensis). This underutilized resource has the potential to yield bioactive compounds of economic and ecological significance. We explore the application of environmentally friendly extraction techniques, including supercritical fluid extraction (SFE), microwave-assisted extraction (MAE) and ultrasound-assisted extraction (UAE), to harness the bioactive potential of rubber seeds. Our research encompasses a comprehensive analysis of the extracted compounds, including their characterization and quantification using state-of-the-art analytical techniques. Environmental and economic sustainability aspects are evaluated, shedding light on the green extraction processes’ ecological footprint and economic feasibility. The paper also delves into these extracted compounds’ diverse applications and utilization prospects, ranging from pharmaceuticals and nutraceuticals to cosmetic and industrial products. We discuss the commercial potential, market opportunities, and emerging trends these sustainable endeavours may shape. In conclusion, this study paves the way for a more sustainable path in harnessing valuable compounds from rubber seed trees, exemplifying the potential for green extraction techniques to play a pivotal role in the journey toward environmental stewardship and economic prosperity.

Producción Científica

: Critically challenging tasks for the researchers are isolating and extracting chief active medicinal phytoconstituents from existing herbal plants. The intricate extraction process usually involves active plant and animal portions separated by selective solvents through various standard procedures. Therefore, most of the products contained the complex metabolites mixtures, making the extraction process involved in separating these products increasingly tricky, thus resulting in lesser yield. Therefore, an alternative strategy suitable for green extraction routes has recently succeeded as a sustainable resource with many advantages like high solvency, low toxicity, and low impact in the environment, biodegradable, and helps recycle consumed solvents without showing any detrimental effects on the environment. : The process of green hydrotrope-assisted extraction process persists a novel and promising methodology that maximizes the yield of phytoconstituents in comparison to the conventional extraction process by the commissioning of a variety of hydrotropes like sodium cumene sulfonate, sodium alkyl-benzene sulfonates, and sodium butyl mono-glycol sulfate, involved in selective extraction of water-insoluble phytoconstituents by the disorganization of the phospholipid bilayers by the hydrotrope, through cell permeabilization, disruption of the cellulosic cell wall and, then possibly the dissolution of the cellular contents. : The central point of this audit is the increase of the surrender of phytoconstituents from herbal plants accomplished by considering green hydrotropic-assisted extraction process, an assignment of carrying out the extraction of herbal plants sanctioning hydrotropes and its component. Using hydrotropes for extracting the phytoconstituents has imperatively highlighted the conveyance frameworks of separated extricated phytoconstituents from herbal plants and encourages the forwarding of their bioavailability at distinctive target destinations.

Citrus by-products valorization using deep eutectic solvents – A review

Synergy of in-situ formation of carbonic acid and supercritical CO2-expanded liquids: Application to extraction of andrographolide from Andrographis paniculata

Green, environment-friendly and sustainable techniques for extraction of food bioactive compounds and waste valorization

Comparative LCA of ultrasound-assisted extraction of polyphenols from chicory grounds under different operational conditions

In recent years, there has been growing interest in bioactive plant compounds for their beneficial effects on health and for their potential in reducing the risk of developing certain diseases such as cancer, cardiovascular diseases, and neurodegenerative disorders. The extraction techniques conventionally used to obtain these phytocompounds, however, due to the use of toxic solvents and high temperatures, tend to be supplanted by innovative and unconventional techniques, in line with the demand for environmental and economic sustainability of new chemical processes. Among non-thermal technologies, cold plasma (CP), which has been successfully used for some years in the food industry as a treatment to improve food shelf life, seems to be one of the most promising solutions in green extraction processes. CP is characterized by its low environmental impact, low cost, and better extraction yield of phytochemicals, saving time, energy, and solvents compared with other classical extraction processes. In light of these considerations, this review aims to provide an overview of the potential and critical issues related to the use of CP in the extraction of phytochemicals, particularly polyphenols and essential oils. To review the current knowledge status and future insights of CP in this sector, a bibliometric study, providing quantitative information on the research activity based on the available published scientific literature, was carried out by the VOSviewer software (v. 1.6.18). Scientometric analysis has seen an increase in scientific studies over the past two years, underlining the growing interest of the scientific community in this natural substance extraction technique. The literature studies analyzed have shown that, in general, the use of CP was able to increase the yield of essential oil and polyphenols. Furthermore, the composition of the phytoextract obtained with CP would appear to be influenced by process parameters such as intensity (power and voltage), treatment time, and the working gas used. In general, the studies analyzed showed that the best yields in terms of total polyphenols and the antioxidant and antimicrobial properties of the phytoextracts were obtained using mild process conditions and nitrogen as the working gas. The use of CP as a non-conventional extraction technique is very recent, and further studies are needed to better understand the optimal process conditions to be adopted, and above all, in-depth studies are needed to better understand the mechanisms of plasma-plant matrix interaction to verify the possibility of any side reactions that could generate, in a highly oxidative environment, potentially hazardous substances, which would limit the exploitation of this technique at the industrial level.

Green extraction processes from renewable biomass to sustainable bioproducts

Sequential extraction and separation using ionic liquids for stilbene glycoside and anthraquinones in Polygonum multiflorum

Process Integration and Intensification

Design of experiments for green and GRAS solvent extraction of phenolic compounds from food industry by-products - A systematic review

Application and mechanism of ultrasonic-assisted extraction of ginkgo flavonol glycosides with natural deep eutectic solvent-based supramolecular solvents

Objective: To make full use of the flavonoids in Dendrobium officinale flowers, a green and efficient extraction process was developed. Methods: Taking the yield of flavonoids from Dendrobium officinale flowers as an index, using new deep eutectic solvents, based on single factor experiments and response surface methodology, the extraction process of total flavonoids was optimized. And macroporous adsorption resins were used to investigate the recycling capacity of DESs. Results: DES composed of choline chloride and ethylene glycol (molar ratio 1:4) had the highest yield. The yield reached 22.457 mg/g under the optimal extraction conditions (water content 18.9 %, temperature 88.2 ℃, liquid-solid ratio 23.3:1 mL/g, time 38.0 min). The adsorption rate and desorption rate of ADS-8 for total flavonoids were 78.32 % and 83.55 %, respectively, and the recycling rate of recovered DES reached 95.47 %. Conclusion: The deep eutectic solvent is an efficient and green method that could be recycled to extract the total flavonoids from Dendrobium candidum flowers.

A green hybrid extraction process for thiophene, quinoline and indole recovery from light hydrocarbon fractions