SU‐E‐T‐678: Monte Carlo Investigation on Dose Perturbations in the Lung Due to Constant Magnetic Fields during MRIgRT

Abstract

Purpose: Magnetic resonance image‐guided radiotherapy (MR‐IGRT) has emerged as a promising new technology to reduce tumor position uncertainty during photon radiotherapy treatments of lung cancer. MRIGRT improves upon traditional IGRT techniques by providing real‐time intrafraction imaging of tumor motion. However, the use of MRI during beam delivery complicates treatment planning since the magnetic field will perturb the radiation dose distribution especially in fields prescribed in heterogeneous regions of the body such as the lung. In this study we used Monte Carlo methods to investigate the magnetic field effects on dose distributions near interfaces of high‐ and low‐density regions where the influence of magnetic fields will be significant. Methods: The Monte Carlo code EGS4nrc was used for all simulations performed in this study. We investigated dose distributions from both Co‐60 and 6‐MV photon beam energy spectra in simple heterogeneous phantoms. The phantoms consisted of alternating slabs of PMMA and air or lung material with different thicknesses. Homogeneous transverse magnetic fields of varying strengths were applied to the phantom during the simulations. Results: Large perturbations in the dose distributions near PMMA‐air or PMMA‐lung interfaces were recorded when a transverse magnetic field was applied to the phantom, which can be attributed to electron return effect. It was demonstrated that the size of the perturbation at an interface depends not only on the magnetic field strength, but also on the primary photon beam energy spectrum and the length of the air cavity within the phantom. Conclusions: Preliminary results demonstrated that magnetic fields alter the delivered dose distributions near interfaces of high‐ and low‐density regions. Therefore, accurate planning for MR‐IGRT treatments of lung cancer may need to consider magnetic field effects on the dose distribution. Future work will use Monte Carlo methods to investigate dose perturbations due to magnetic fields in 4D patient geometry.