Abstract
Objective:To compare the effectiveness of pain relief of Sucralfate and lidocain antacid 50:50 solution in post esophageal variceal band ligation pain.Methods:All patients who had under gone Esophageal Variceal Band Ligation (EVBL) were included in the study. Patients un-willing to be included in the study or those who didn’t have post EVBL pain were excluded. Patients with post EVBL pains were divided into two groups: one group was given sucralfate and other was given lidocaine: antacid 50:50 solution. Both were inquired about the duration of the pain relief after the medication. The results were analyzed on SPSS 23. Independent samples T-test was performed to find out whether the difference in duration of pain relief was significantly different in the two groupsResults:Out of 110 patients who have EVBL, 66(60.00%) had pain and 44(40.00%) were pain free. In the pain group 46 (69.7%) were given sucralfate and 20 (30.3%) were given lidocain: antacid 50:50 solution. Mean duration of pain relief in two groups was 2.78 (SD ± 2.096) and 2.5 days (SD ±. 0.76) respectively. Independent samples T-test results revealed that there was no statistically significant difference in the duration of pain relief between these two groups with p value 0.426.Conclusion:Both Sucralfate and Lidocain: antacid 50:50 solutions are effective in relieving the post EVBL pain. However, no statistically significant difference in duration of pain relief was detected in separate groups of patients treated with either treatment.
Highlights
Upper Gastrointestinal bleed secondary to esophageal varices is a life threatening situation in Decompensated Chronic Liver Disease (DCLD)
Post Esophageal Variceal band ligation pain is a common complication, mostly it is mild to moderate in intensity but may be severe in few cases
Keeping in view two medicines were tried in this study i.e. sucralfate and lidocain: antacid 50:50 solution to find out the effects to relieve the pain
Summary
Upper Gastrointestinal bleed secondary to esophageal varices is a life threatening situation in Decompensated Chronic Liver Disease (DCLD). With single bleed mortality increased to 20%, rebleed in 40% in six weeks’ time and 75% at one year.[1] Injection sclerotherapy revolutionized the treatment and remain only successful mode of therapy for many years.[2] question rose because of procedure related complications like rebleeding from large ulcers, stricture formation especially when performed with lesser interval.[3] It was replaced with Esophageal Variceal band ligation because of lesser complications like transient dysphagia, small ulcers and less risk of rebleed.[4,5]. Post Esophageal Variceal band ligation pain is a common complication, mostly it is mild to moderate in intensity but may be severe in few cases. It settles itself but may require some intervention to relieve it. Keeping in view two medicines were tried in this study i.e. sucralfate and lidocain: antacid 50:50 solution to find out the effects to relieve the pain
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