Successful treatment of severe acrodermatitis continua of Hallopeau with guselkumab.

Background: Tuberculosis (TB) is a global public health concern. The new challenge in TB control is the development of TB multi drug resistance (MDR-TB). Indonesia ranks 8th highest in the incidence of MDR-TB with 8,900 MDR-TB cases in 2004. A case was defined as MDR-TB if the Mycobacterium tuberculosis was resistant to rifampicin dan isoniazid. This study aimed to determine the factors affecting the success of multi drug resistance (MDR-TB) tuberculosis treatment. Subjects and Method: This was an analytic observational study using case control design. The study was conducted at Dr. Moewardi Hospital, Surakarta, Central Java, Indonesia, in October 2014. The case population were MDR-TB patients visiting Dr. Moewardi Hospital for TB treatment from 2011 to October 2014. A sample of 84 TB cases consisting of 26 patients who dropped out, defaulted, or died, and 58 patients who successfully completed TB treatment, were selected for this study. The independent variables were sex, age, marital status, nutrional status, education, employment status, drug side effect, family support, and distance to health facility. The dependent variable was success of treatment. The data were collected by direct interview, questionnaire, and medical record. Logistic regression was employed for data analysis. Results: Age (OR= 0.93; 95% CI = 0.88 to 0.97; p=0.004) and drug side effect (OR= 6.84; 95% CI = 2.50 to 18.74; p<0.001) affected the success of TB treatment and statistically significant. Sex (OR= 0.66; 95% CI = 0.17 to 2.58; p=0.556), education (OR=0.90; 95% CI = 0.52 to 1.58; p=0.724), employment status (OR= 0.87; 95% CI = 0.59 to 1.28; p=0.485) affected the success of TB treatment but statistically not significant. Conclusion: Success of TB treatment is affected by age and drug side effect. Keywords: success of treatment, tuberculosis, multi drug resistance. Correspondence:Â Elisabeth Ria Widyasrini. Public Health Center, Klaten, Central Java. Email: lisabalkesmasklaten@gmail.com, mobile: +628990833108. Journal of Epidemiology and Public Health (2017), 2(1): 45-57 https://doi.org/10.26911/jepublichealth.2017.02.01.05 Â

Tuberculosis (TB) is an infectious disease that poses one of the major threats to humans. To deal with all threats from tuberculosis, WHO has developed a TB control strategy known as the DOTS strategy to improve the success of TB treatment with the indicator used being cured and complete treatment. The success of treatment is influenced by internal and external factors such as smoking. This study aims to determine the relationship of smoking behavior with the success of tuberculosis treatment at community health center of JoharBaru Central Jakarta in 2016. This research was conducted by Cross-Sectional non-experimental quantitative method. Population and sample are adult tuberculosis patients registered at community health center of JoharBaru Central Jakarta in 2016. Samples are selected by using Simple Random Sampling. The data were collected by interview using questionnaire. Data analysis using SPSS with Chi-Square test. Result: There were 45 respondents (80,4%) succeed in tuberculosis treatment with 25 people (83,9%) of respondents who did not smoke. Results of statistical tests using Chi-Square test obtained value P = 0.69 (&gt;0,05). There is no relation between smoking behavior with the success of tuberculosis treatment at community health center of JoharBaru Central Jakarta in 2016. Keywords:Smoking Behavior, Success of Tuberculosis Treatment

To determine the outcomes and factors associated with postpartum haemorrhage (PPH) treatment with condom-catheter uterine balloon tamponade (C-UBT). Prospective observational study. A secondary healthcare facility in Nigeria. Women with PPH refractory to first-line treatment. Demographic and clinical characteristics were compared in women with successful and unsuccessful treatment. Univariate and multivariate logistic regression analyses were used to examine the association of these characteristics with successful treatment. The success rate of C-UBT, factors associated with success, and maternal morbidity rates in both successful and unsuccessful treatment groups. Overall, 203/229 (88.6%) women had successful treatment. Women with successful treatment had lower mean blood loss (1248.8±701.3ml versus 3434.6±906.6ml; P<0.0001), lower occurrence of blood transfusion [139 (68.5%) versus 26 (100%); P<0.0001], lower intensive care unit admission rates [5 (2.5%) versus 20 (76.9%); P<0.0001], and lower occurrence of infectious morbidities [3 (1.5%) versus 7 (26.9%); P<0.0001]. In the regression model with two factors, caesarean section (adjusted odds ratio, aOR0.17; 95% confidence interval, 95%CI 0.07-0.40) was associated with lower success rates compared with vaginal delivery. In the regression model with three factors, advanced maternal age (aOR0.31; 95%CI 0.11-0.90) and caesarean section (aOR0.17; 95%CI 0.07-0.41) were associated with lower success rates in comparison with younger maternal age and vaginal delivery, respectively. Second-line PPH treatment with C-UBT is effective, and is associated with low maternal morbidity rates. Advanced maternal age and caesarean section are associated with lower success rates. Condom-catheter tamponade is a useful second-line treatment modality for intractable postpartum haemorrhage.

Relation of clinical success in coronary brachytherapy to dose

The immune-compromised condition due to type 2 diabetes mellitus (T2DM) can increase the risk of treatment failure in patients with drug resistant-tuberculosis (DR TB). This study aims to determine the effect of T2DM and treatment regimen on the success of DR-TB treatment in Riau Province in 2014-2018. The design of this study was retrospective cohort using data of DR TB which were recorded in 01 DR TB form, 03 DR TB form, DR TB medical records and e TB manager at the DR TB referral hospital of Arifin Achmad Regional General Hospital and 7 sub-referral hospitals in Riau Province in 2014-2018. The independent variables were the type 2 DM and treatment regimen. The covariate variables were demographic factors namely, age, sex, marital status, occupation, education, residence category, clinical factor of previous TB treatment history, and medication adherence. The dependent variable was the success of DR TB treatment. The samples of this study were 146: 50 samples of exposed group (T2DM) and 96 samples of non-exposed group (Non T2DM). The survival analysis was used for data analysis. The results showed that 54.79% patients were successfully treated. The probability of 50% success of treatments in both T2DM and nonT2DM using old regimen (conventional method) occurred on the 729 th day. While, the probability of 50% treatment success in both T2DM and Non T2DM groups using new regimen (STR/ shorter regimen) occurred faster on the 272 th day. The risk of T2DM group with the new regimens in the treatment of DR-TB was 10.66 times (95% CI 3.23-35.12). Whereas, the treatment on NonT2DM group with old regimen with marital status that was controlled showed a significant statistic value with value p&lt; 0.001. Conclusion: The use of new regimen accelerated the healing time and increased the successful treatment of patients with T2DM with DR TB.

Objective To analyze the recurrence and risk factors of pulmonary tuberculosis (TB) cases after successful initial treatment in Beijing. Methods A retrospective cohort study was conducted. The data of pulmonary TB cases with successful initial treatment in Beijing during 2015–2017 were collected from TB information management system. The medical records and infectious disease report cards registered or reported before December 31, 2020 were collected to find recurrent TB cases and survival analysis was performed. The recurrence of TB was estimated by using life-table method, Kaplan-Meier method was used for univariate analysis of recurrence, log-rank method was used for comparison between groups, and time-dependent Cox regression model was used for multivariate analysis. Results Of the 8 503 TB cases with successful initial treatment enrolled in Beijing, 253 (2.98%) had recurrence, with a recurrence rate density of 8.13/1000 person-years, in which 88.54% (224 cases) had recurrence within 3 years, and 3.57% had recurrence within 5 years. Multivariate analysis based on univariate analysis showed that, lung cavity (adjusted Hazard ratio, aHR =1.592, 95% CI: 1.166–2.172, P=0.003), time-dependent covariates such as age (aHR=1.004, 95% CI: 1.001–1.008, P=0.008), passive treatment (aHR=1.200, 95% CI: 1.008–1.428, P=0.040), being etiologically positive (aHR=1.154, 95% CI: 1.034–1.289, P=0.011) were the independent risk factors for TB recurrence. Conclusion We should strengthen the follow-up and management of pulmonary TB patients after successful treatment, and conduct targeted intervention for groups at high-risk for TB recurrence. Health education for the general people should be strengthened, and early detection and early treatment of TB cases should be performed to reduce TB recurrence.

Examination of Treatment Duration, Treatment Success and Obstetric Results According to the Vaginismus Grades

Factors Associated With Response to Biofeedback Therapy for Dyssynergic Defecation

BACKGROUND: In the low TB incidence countries cases have been concentrated in the social risk groups. AIM: To identify factors associated with TB death. METHODS: Analysis of the data from the National TB Register concerning cases of death from TB (D) and patients with treatment success (TS), 2004-2015. χ2 and F tests to assess significance (Si) and the multivariate logistic regression (MLR) were used. P RESULTS: 2,176 D and 71,954 TS were notified. The percentage of men in D was 75.3%; in TS 65.2% (Si). Mean age of D was 62.8 yrs (SD±15.9); of TS 51.8 (SD±17.3) (Si). Homelessness occurred in 5.7% of D and in 2% of TS; 62.5% of D and 46.8% of TS were unmarried (Si). 16.4% of D and 10.4% of TS had TB therapy in the past (Si). The past treatment was incorrect in 20.4% of D and in 11.8% of TS (Si). 2.7% of D and 4.7% of TS had extrapulmonary TB (Si). TB was culture confirmed in 84.2% of D and in 63.7% of TS (Si). Sputum smears were positive in 62.2% of D and in 38.6% of TS (Si). Caseous pneumonia occurred in 5.5% of D and in 1.2% of TS; infiltrative TB in 84.3% of D and in 92% of TS; fibrocavernous in 3.9% of D and in 1.2% of TS; miliary in 2.5% of D and in 0.3% of TS (all Si). 4.1% of D and 0.2% of TS had MDR-TB (Si). In MLR male sex, older age, homelessness, unemployment, pulmonary TB, having otherthan infiltrative form of pulmonary TB, MDR-TB were the independent risk factors for TB death. CONCLUSIONS: In the group of TB death there are phenomena which indicate belonging of the patients to the social risk groups as well as TB diagnosis delay. Screening for TB in vulnerable groups could be considered to prevent delay in diagnosis and death from TB.

We found low certainty evidence that transcranial direct current stimulation may improve pain intensity compared to sham stimulation. We could not reach any conclusions on the efficacy of any other interventions on pain intensity, pain frequency, and treatment success. The certainty of the evidence was very low due to the low numbers of studies and participants in each comparison and clinical heterogeneity amongst the studies. While no serious or total adverse events were elicited explicitly with any of the treatments studied, the reported events were very low. The certainty of the evidence for all comparisons was very low, so no conclusions can be drawn.

Hepatitis C treatment and quality of life – You can’t always get what you want, but you might get what you need

Introdaction: Pulmonary TB is an infectious disease caused by the bacillus Mycobacterium tuberculosis. Transmission is through the air and the source of transmission is TB patients whose sputum contains TB germs. The success of treatment is the result (output) of treatment carried out by TB patients, consisting of complete recovery and treatment marked by a negative sputum examination result at the end of treatment. Family support is the attitude, action, and acceptance of sick sufferers. Objective: to determine the relationship between family support and the success of pulmonary TB treatment at the Jombang Hospital polyclinic. Design: using an analytical design using a cross-sectional approach. The number of respondents 30 using purposive sampling, purposive method and in accordance with the inclusion criteria. The measuring instrument used is a questionnaire that has been tested for validity and reliability. The analysis used is the univariate analysis of the frequency distribution and the bivariate Chi¬_Square test.Results: The results showed that 21 people declared good family support and recovered but the results of the Chi_Square test were H0 accepted which means that there is no relationship between family support and the success of pulmonary TB treatment with p-value = 0.021 (&lt; 0.05). Conclusion: it is hoped that the family can provide support to patients with pulmonary TB for the success of their treatment.

The aim of the study was to examine the efficiency of psycho-education of candidates for the IVF in stress, anxiety and depression decreasing, and the impact of the psycho educative techniques on the successfulness of the treatment. A random sample of 64 candidates for IVF treatment is divided in two groups: control group without psycho-education (32 candidates) and intervention group of 32 candidates included in psycho-education. Depression, anxiety and stress scale (DASS) was used as a psychometric test. It's a multiple choice, self-reported inventory for measuring the levels of stress, anxiety and severity of depression. For statistic evaluation SPSS software was used. The study shows that the intervention group included in psycho-education has a signifycantly lower scores on stress (t = 3.201, p < 0.05) and anxiety (t = 2.311, p < 0.05). The scale of depression did not show differences in the two compared groups. However, the success of the IVF treatment is more common among candidates that were included in psycho-education. In our country, psycho-education of candidates for in vitro fertilization is not systematically integrated in the treatment. The study showed the efficiency of psycho-education in anxiety and stress decreasing, as well as significant impact in the successfulness of the treatment. It was pointed out that psychological support of candidates for IVF is important for the lessening of the negative emotional reactions of candidates as well as for the successfulness of the treatment.

Examined here is the degree to which particular aspects of treatment experience in the inpatient psychotherapy of children and adolescents correlate significantly with the actual success of treatment. Data of 95 patients hospitalised between 2002 and 2006 in the Department of Child and Adolescent Clinical Psychotherapy at the NLKH Tiefenbrunn were analysed. To assess the relationships multiple regression analyses were carried out, whereby the dependent variable was on the one hand, the retrospective estimate of treatment success by the patients by means of the Questionnaire to Assess Treatment (Fragebögen zur Beurteilung der Behandlung/FBB), and on the other, the difference on the General-Severity-Index (GSI) of the Symptom Checklist 90-R (SCL-90-R) between the time of admission and release from hospital. Patients' experience of treatment was assessed by MEANS OF THE WARD EXPERIENCE QUESTIONNAIRE (STATIONSERFAHRUNGSBOGEN/SEB) BY SAMMET AND SCHAUENBURG (1999). The direct measurement of success (FBB-P-Scale Success of Treatment) correlated highly significantly with the SEB scales Expectation of Self-Efficacy, Individual Therapeutic Relationship, Atmosphere among Co-Patients, Group Cohesion, Relationship to Therapy Team, Intensity of Treatment, and with the Difference in the Estimate of Individual Therapeutic Relationship between Patient and Therapist. The indirect measure of success also correlated highly significantly with the Atmosphere among Co-Patients and the perceived Expectation of Self-Efficacy. The relationship between the Relationship to Therapy Team was also significant at the 5% level. In the subsequent regression analyses the SEB scales explained 51% of the variance between the retrospective estimates of success (FBB). The subscales Relationship to Therapy Team (beta= 0.47, t(df) = 4.15(84), p < .01) and Expectation of Self-Efficacy (beta = 0.32, t(df) = 3.30(84), p < .01) proved to be significant predictors of treatment success. Using the difference in the GSI values on the SCL-90-R as the dependent variable, the SEB scales explained 23% of the variance in treatment success, whereby Atmosphere among Co-Patients was the only significant individual subscale (beta = 0.35, t(df) = 2.63(84), p < .01). The success of inpatient psychotherapy treatment among children and adolescents in the sample studied correlated significantly with particular aspects of treatment experience. In this connection, the reduction in symptoms apparent in the comparison of values at admission with those at release seems to be primarily related to the Atmosphere among Co-Patients, whereas the success of treatment as estimated directly by the patients correlates more strongly with Relationship to Therapy Team and Expectation of Self-Efficacy. Due to the correlative design of the study, the issue of causality could not be completely resolved.

Preliminary experience and possible predictors of successful mirabegron treatment for overactive bladder