Abstract
BackgroundSalmonella species can be rarely isolated from periprosthetic joint infections, however when present, are usually part of a severe septic clinical picture.Case presentationsTwo patients presented with late infected hip replacements to our institution. The first patient with multiple comorbidities had a confirmed Salmonella Enteridis infection with an abscess in the groin, with loosening of both components. He underwent a successful one stage cemented revision hip replacement, followed by 6 weeks of antibiotic therapy (ciprofloxacin). He had no recurrence or complications. The second patient was admitted in a septic condition with ARDS to the Intensive Care Unit 7 years following an uncemented total hip replacement. From an ultrasound guided hip aspirate Salmonella cholerae-suis was isolated. He underwent a successful a two-stage revision hip replacement.ConclusionsSuccessful treatment of such potentially life threatening infections is achievable using modern orthopaedic techniques and close collaboration with the infectious diseases specialists.
Highlights
Salmonella species can be rarely isolated from periprosthetic joint infections, when present, are usually part of a severe septic clinical picture.Case presentations: Two patients presented with late infected hip replacements to our institution
Debridement and retention can be successful providing that an antibiotic with efficacy on biofilm bacteria is used [6]
In the English literature, there have only been 10 reported cases of post-operative infections caused by Salmonella species after total hip replacement [7,8,9,10,11,12]
Summary
Salmonella species can be rarely isolated from periprosthetic joint infections, when present, are usually part of a severe septic clinical picture.Case presentations: Two patients presented with late infected hip replacements to our institution. Several Salmonella species have been reported to cause periprosthetic joint infection. As per the susceptibility of the organism intensive, intravenous, combined antibiotic treatment of 3 × 600 mgs of clindamycin and 3 × 400 mgs of ciprofloxacin was initiated for the first 72 hrs, and oral ciprofloxacin was given for a further 6 weeks, in the dose of 2 × 500 mgs.
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