Successful pregnancy following in vitro fertilization-embryo transfer in a woman with diminished oocytereserve despite a slow rising beta human chorionic gonadotropin level

Abstract

Purpose: To present another rare case of a live pregnancy despite an inappropriate rising serum beta hCG level. Materials and Methods: A woman with diminished oocyte reserve had an in vitro fertilization (IVF) cycle, so the precise day of ovulation was known. Results: Despite an inappropriate doubling time for the serum beta-hCG level and a crown rump length sac size discrepancy (small sac), an apparently healthy fetus with no apparent anomalies has passed the second trimester. Conclusions: Despite the risk of ectopic pregnancies with slow rising hCG levels, and the generally very low chance of a successful viable pregnancy, one may need to not be too quick to terminate the pregnancy with methotrexate.