Abstract
Major depressive disorder (MDD) is one of the most disabling disorders and the one that most contributes to disability. When it occurs in older people, it is an additional burden to their potential physical and cognitive deficiencies, making MDD an important public health problem that supposes a large investment in health. There is a clear lack of consistency between the subtypes of depression found in the literature, ranging from two to seven classes, with three being the most commonly found non-melancholic, melancholic and psychotic, or putative psychotics. The aim of this research is to add knowledge to the profiles of depressive symptoms in a representative sample of older Spanish people, and to study the possible relationship of these symptom profiles with variables that have traditionally been related to depression. Spanish data from the sixth wave of SHARE were used, with 612 Spanish older adults living in Spain. A routine of several LCAs with a different number of classes was performed to answer this first aim to classify Spanish adults with depression symptoms. The results pointed out the presence of three different classes among the participants in the study: psychosomatic (11.12%), melancholic (14.21%), and anhedonic (74.67%). This work represents a step forward to understand the heterogeneity of major depressive disorder, facilitating the diagnosis, and subsequent treatment of older adults.
Highlights
Major depressive disorder (MDD) is one of the most disabling disorders worldwide [1], being the one that most contributes to disability, with a 7.5% global average (WHO, 2017) representing 4.3%of the global disease burden [2] MDD has a prevalence of 14% among people 65 years or older [3,4].Older adults generally do not seek treatment [5] which, added to their potential physical and cognitive deficiencies, makes MDD an important public health problem that supposes a large investment in health
Best fitting solution should be chosen as the one with the lowest information criteria (BIC, ABIC, and AIC), largest entropy value, and statistically significant Lo–Mendell–Rubin test (LMR) and Bootstrapped Likelihood Ratio Test (BLRT) tests
Spanish old adults with a relative high ratio of depressive symptoms, and see how these profiles related to variables associated with depression
Summary
Major depressive disorder (MDD) is one of the most disabling disorders worldwide [1], being the one that most contributes to disability, with a 7.5% global average (WHO, 2017) representing 4.3%of the global disease burden [2] MDD has a prevalence of 14% among people 65 years or older [3,4].Older adults generally do not seek treatment [5] which, added to their potential physical and cognitive deficiencies, makes MDD an important public health problem that supposes a large investment in health. Major depressive disorder (MDD) is one of the most disabling disorders worldwide [1], being the one that most contributes to disability, with a 7.5% global average (WHO, 2017) representing 4.3%. Of the global disease burden [2] MDD has a prevalence of 14% among people 65 years or older [3,4]. Older adults generally do not seek treatment [5] which, added to their potential physical and cognitive deficiencies, makes MDD an important public health problem that supposes a large investment in health. Sneed, J.R., et al found two types of depression, vascular and non-vascular depression [9], in two different samples of community-dwelling old people with a diagnosed previous major depressive episode
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