Abstract
Subclinical Portosystemic Encephalopathy and Changes of Lung Stream Course in Children and Juveniles with Portal Hypertension due to Prehepatic Block A subclinical encephalopathy was found by means of psychometric tests, EEG and VECP in 50% of children and juveniles with surgically and conservatively treated portal hypertension due to prehepatic block (n = 36). The patients with subclinical encephalopathy had visually qualified bilateral symmetric hyperintensity in the basal ganglia of the brain in the T<sub>1</sub>-weighted image. The changes of the signal intensity correlated with the function of the portal systemic shunt and/or the severity of the liver dysfunction. Decreased diffusion capacity (< 80% of reference input) could be measured in 75% of shunt patients (n = 20) 16 years after shunt operation with non-invasive methods by means of spirometry, body plethysmography, determination of diffusion, analysis of blood gases, ECG, and ECHO. This decreased diffusion capacity can already be considered as a reference to changes of lung stream course, even if the patients are asymptomatic.
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