Subjective measurement of the Stiles-Crawford effect of the first kind with variation in accommodation.

Abstract

To measure the Stiles-Crawford effect of the first kind (SCE-I), corresponding to central vision, with innovative technology to evaluate changes in the directionality and photoreceptor alignment with accommodation. A uniaxial Maxwellian system (spot size in pupil 0.5mm diameter) was employed, incorporating a spatial light modulator to flicker at 2Hz between two 2.3° fields corresponding to test (peripheral pupil) and reference (pupil centre) positions. Participants determined thresholds at 13 positions along the horizontal pupil meridian by indicating if the test field was brighter or dimmer than the reference field. Thresholds were determined by a staircase procedure after four reversals at each pupil location. After pupil dilation, seven emmetropes were tested at 0 D to 6 D accommodation stimulus levels in 2 D intervals. Data were fit by the Gaussian function, both when the fits were unforced or forced to pass through the sensitivity expected for the reference point. Directionality (ρ) and peak location values were determined for unforced and forced fits. Regression slopes for ρ as a function of accommodation stimulus were not significant. There was a tendency for to shift temporally with increasing accommodation across the 6 D stimulus range. This was not significant for regression fitting (-0.059mm/D, R2 =0.06, p=0.20), but a paired t-test for 0 and 6 D stimuli showed a weakly significant change of 0.62mm (p=0.05). The differences between the two fitting approaches were small and non-significant. Directionality did not change with accommodation, but the pupil peak location showed a significant temporal shift of approximately 0.62mm with 6 D accommodation stimulus. It is possible that substantial changes in the directionality and a shift in the direction of peak location might occur at very high levels of accommodation.