Abstract
Purpose:To assess the correlation between mean lethal radiation doses (Do) with NMR water proton spin lattice relaxation time (T1) in different phases of Hela cells.Methods:Analysis of T1 with Do was assessed in M, G1, G2 and S‐phase at energies of 220 kVp, 280 kVp and 1.25 MeV (Co‐60).Results:T1 against Do in M, G1, G2, and S phase at 220 kVp yield a correlation of 0.80. At 280 kVp and 1.25 MeV the correlation is 0.77 and 0.82 respectively.Conclusion:It appears that T1 value decreases from M phase (1020 ± 84 ms) to S phase (534 ± 43 ms). The Do values increases from M phase to S phase. The variation in T1 and Do in different phases of the cell cycles provide a clue to time the mitotic phase at the radiation treatment time. It appears that T1 value decreases from M phase (1020 ± 84 ms) to S phase (534 ± 43 ms). The Do values increases from M phase to S phase. The variation in T1 and Do in different phases of the cell cycles provide a clue to time the mitotic phase at the radiation treatment time.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
