Studying the relevance of psoriasis with increased artery intima–media thickness, in patients of skin disease clinics of kashan medical science university in 2016

Abstract

Aim: Psoriasis is a prevalent chronic skin disease, and evidence shows that psoriasis is considered as a risk factor for increased cardiovascular diseases. Consequently, this study purpose is an assessment of the relationship between psoriasis and carotid intima–media thickness (CIMT). Materials and Methods: The case–control study was conducted on 31 patients developed psoriasis, referred to the skin health-care centers of Kashan in 2016, and 31 healthy controls. Demographic data, disease duration, Psoriasis Area and Severity Index, and Carotid Artery Intima–Media Thickness were measured in each group of patients and compared. Data were entered into SPSS 16 software and analyzed using Chi-square, “Kolmogorov–Simonov” “Leven t-test,” univariate analysis of variance, and Pearson correlation tests. Results: The patients aged in case group was 10 ± 33 and in control group was 10 ± 32. CIMT values were obtained higher in patient group than in control group, but the difference was not significant (P = 0.44). CIMT results showed a significant increase in male than female patients (P = 0.02). In the present study, no relationship between CIMT and age of disease development and PASI index was observed which indicated the disease severity. Conclusion: In this study, according to the Pearson's correlation, a positive correlation was observed between the mean CIMT and age and also duration of the disease in patient group. Any correlation between psoriasis and CIMT and also between the CIMT and age of onset of the disease and PASI score was not found.