Abstract

The existing knowledge on the effect of air cleaners in reducing different indoor impurities and health symptoms in real-life applications is still insufficient. PUHHO study aimed to fill this knowledge gap with a blinded intervention study in 18 primary school classrooms. The study was conducted during 8 weeks with 2 weeks without air cleaner, 3 weeks with air cleaner in full operation (filtration) with moderate airflow (200 - 400 m3/h) and 3 weeks sham operation (air cleaner blowing air without filtration). The latter two interventions were conducted in a blinded and mixed setup. Small, but statistically non-significant reductions in particulate matter levels (PM2.5; particulate matter with diameter less than 2.5 µm and PM10; diameter of particles less than 10 µm) were observed when comparing air cleaner filtration to air recirculation alone (sham operation). The use of air cleaners had no significant effect on the level of total volatile organic compounds (TVOC). Air cleaners did not have significant effect on the microbial levels or on the microbiome of the classrooms. Filtration by air cleaners was found to statistically significantly reduce upper (4.0%) and lower airway (2.5%) and other (4.0%) symptoms, but a nearly equivalent effect was observed with air recirculation alone.

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