Abstract
The influence of fenugreek injected (IP) on male fertility by using following tests (measurement of testosterone level, sperm viability, activity, motility and abnormalities) and on GOT, GPT, Al.ph. and Lipid profile status was studied in normal and alloxan diabetic mice.Alloxan diabetic mice were injected with Trigonella extract for 5 weeks at a dosage of 2g/kg body weight. The Alloxan diabetic mice exhibited enhanced decrease significantly in glucose level in serum. Increased testosterone level and decreased dead sperms, abnormalities and increase motility , decrease in GOT, GPT, AL.PH. and lipid profile, in alloxan diabetic mice
Highlights
Trigonella fraenum graecum is traditionally used to treat disorders such as diabetes, high cholesterol, wounds, inflammation, and gastrointestinal ailments [17].Recent studies suggest that fenugreek and its active constituents may possess anticariogenic potential [15,20].Trigonella seeds and some of its fraction have a hypoglycaemic effect in experimentally induced diabetes [17, 21]and have hypercholesterolemic activity in rats [10,12]
Plant materials: Fenugreek seeds were purchased from the local market and identified in a Biotechnology Research
Induction of Diabetes: Diabetes was induced by a single intraperitoneal injection of alloxan monohydrated (5% w/v) in physiological saline at a dose of 150 mg/kg body weight in a volume of
Summary
Trigonella fraenum graecum (fenugreek) is traditionally used to treat disorders such as diabetes, high cholesterol, wounds, inflammation, and gastrointestinal ailments [17]. Recent studies suggest that fenugreek and its active constituents may possess anticariogenic potential [15,20]. Trigonella seeds and some of its fraction have a hypoglycaemic effect in experimentally induced diabetes [17, 21]. Have hypercholesterolemic activity in rats [10,12]. Fenugreek has very important roles to improve fertility due to it contain diogesine that considered
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