Abstract
Vasaka or Adhatoda vasica (L.) Nees is a well-known plant medication in Ayurvedic and Unani medicine. Cough, whooping cough, cold, and clinging phlegm in the mouth, throat, chest, or breast have been traditionally treated using Adhatoda vasica nees. The present study aimed to evaluate Adhatoda vasica's phytochemical analysis and antimicrobial activity. The preliminary phytochemical screening of alkaloids, steroids, saponins, phenols, and terpenoid yielded positive results. The antibacterial activity of ethanol and leaf extracts of Adhatoda vasica was investigated in this study. Based on the data presented herein, the largest zone of inhibition was found to be against Pseudomonas aeruginosa. The antifungal activity of Aspergillus clavatus was proven to have the maximum zone of inhibition. As a result, the current method may be effective in identifying new bioactive compound for the development of novel medications. Thus, it may be used as a strong antimicrobial agent against Pseudomonas aeruginosa pathogens.
Highlights
Medicinal plants, which are the basis of traditional medicine, have been the subject of much pharmacological research in recent decades
Phytochemical results revealed the presence of various bioactive auxiliary metabolites in leaf ethanol concentrates of Adhatoda vasica
The findings showed that the pure ethanol extracts of A. vasica leaves provided the greatest antibacterial activity against the microorganisms examined by using the agar-well diffusion method
Summary
Medicinal plants, which are the basis of traditional medicine, have been the subject of much pharmacological research in recent decades. Adhatoda vasica native range is Asia and is a well-known plant in Ayurveda and Unani systems of medicinal plant Various parts of this plant have been used to treat several ailments as herbal remedies for many porpoises, e.g., cold, cough, whooping cough, chronic bronchitis, fever, jaundice asthma as a sedative expectorant, diarrhea, and dysentery, as well as inflammatory rheumatic diseases. Medicinal plants are considered a potential source of new compounds of therapeutic value and important sources of new compounds in drug development [7]. These plants make many chemical compounds to protect themselves against fungi, and bacteria, this act in the same way on the human body as allopathic drugs [8, 9].
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