Abstract

Study Objective: The aim of the study was to evaluate the feasibility and safety of laparoscopic nerve-sparing radical hysterectomy as well as its impact on voiding function and compare that with the patients who underwent traditional radical hysterectomy without nerve sparing.Design: Retrospective study.Setting: Department of Gynecology, Changzhou Second People's Hospital, Jiangsu, PR China.Patients: 58 patients with cervical cancer of stages IB to IIA who were hospitalized and operated on at the Department of Gynecology of the Changzhou Second People's Hospital Of Nanjing Medical University in China between September 2007 and September 2009 were analyzed.Intervention: 32 were in the non-nerve-sparing group and 26 were in the nerve-sparing group.Measurements and Main Results: Laparoscopic nerve-sparing radical hysterectomy was completed successfully and safely in all of the patients. Ten (38%) patients had the PVR of less than 100 ml at the initial removal of the catheter. On the fourteenth day, 73% of the patients had the PVR of less than 100 ml. The estimated blood loss during operation of nerve-sparing group and non-nerve-sparing group were (514±287) ml and (456±218)ml, with no significant difference (P>0.05). Compared to the patients in non-nerve-sparing group, the patients in nerve-sparing group had a longer operative time(270±84min vs. 212±65min, P<0.05), shorter postoperative bladder function recovery(9.3±2.2days vs. 16.8±5.9 days, P <0.01).Conclusion: Laparoscopic nerve-sparing radical hysterectomy appears safe, adequate, and feasible in our population with satisfactory recovery of voiding function in comparison to traditional radical hysterectomy. Study Objective: The aim of the study was to evaluate the feasibility and safety of laparoscopic nerve-sparing radical hysterectomy as well as its impact on voiding function and compare that with the patients who underwent traditional radical hysterectomy without nerve sparing. Design: Retrospective study. Setting: Department of Gynecology, Changzhou Second People's Hospital, Jiangsu, PR China. Patients: 58 patients with cervical cancer of stages IB to IIA who were hospitalized and operated on at the Department of Gynecology of the Changzhou Second People's Hospital Of Nanjing Medical University in China between September 2007 and September 2009 were analyzed. Intervention: 32 were in the non-nerve-sparing group and 26 were in the nerve-sparing group. Measurements and Main Results: Laparoscopic nerve-sparing radical hysterectomy was completed successfully and safely in all of the patients. Ten (38%) patients had the PVR of less than 100 ml at the initial removal of the catheter. On the fourteenth day, 73% of the patients had the PVR of less than 100 ml. The estimated blood loss during operation of nerve-sparing group and non-nerve-sparing group were (514±287) ml and (456±218)ml, with no significant difference (P>0.05). Compared to the patients in non-nerve-sparing group, the patients in nerve-sparing group had a longer operative time(270±84min vs. 212±65min, P<0.05), shorter postoperative bladder function recovery(9.3±2.2days vs. 16.8±5.9 days, P <0.01). Conclusion: Laparoscopic nerve-sparing radical hysterectomy appears safe, adequate, and feasible in our population with satisfactory recovery of voiding function in comparison to traditional radical hysterectomy.

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