Abstract

The angelicin-thymine photoadduct formed by irradiation (365 nm) of an aqueous solution of angelicin and tritiated thymine was isolated by preparative paper chromatography. Reirradiation of this photoadduct at wavelengths shorter than 334 nm splits the adduct, forming again the two parent compounds. A DNA-angelicin combination (8.30 μg angelicin per mg of DNA) was prepared by irradiating (365 nm) an aqueous solution of DNA with3H-angelicin. Reirradiation of this combination at wavelengths shorter than 312 nm releases3H-angelicin.

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