Abstract

The metabolites of the oral anticoagulant phenprocoumon are characterized as the 7,4′ and 6-hydroxyphenprocoumons in human plasma and urine using liquid chromatography and gas chromatography-mass spectrometry. The author's own work and that of others are reviewed and the metabolic stereoselectivity of phenprocoumon and its metabolism is compared with that of warfarin.

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