Abstract
Radioactive tracer methods were used to study the distribution of crocidolite between the upper and lower respiratory tracts after single short inhalation exposures of the “nose only” type. With the UICC standard reference sample of crocidolite, it was found that 50 ± 5% of the deposited asbestos was in the lower respiratory tract. After 30 days the lung content of crocidolite had been reduced to 73% of the initial value. Autoradiography was used to study the distribution of asbestos within the lung immediately after exposure and after 30 days. The clearance of crocidolite from the respiratory tract was also followed by the measurement of radioactivity in faeces.
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