Abstract
The Ugi four-component condensation between methyl o-formylbenzoates 1, anilines 2a– c, isocyanides 3, and trimethylsilyl azide ( 4) afforded the expected Ugi adducts 5a– d, which were cyclized to the title compounds 6a– d upon treatment with sodium ethoxide in ethanol. Starting from aralkyl- or alkylamines 2d– g the Ugi adducts underwent a spontaneous cyclization to tetrazolyl-isoindolinones 6e– j.
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