Abstract

To the Editor: Atrial fibrillation (AF) is the most common, potent, and independent risk factor for ischemic stroke,1 the incidence of which increases with age.2 To determine the influence of advanced age on anticoagulation therapy in elderly patients with AF, a retrospective cohort study of all patients admitted in our department (from 1995 to 2003) was conducted. These patients were >90 years of age and had had an acute stroke. The following parameters were analyzed: age, sex, cardiovascular risk factors and their treatment, and outcome. Among the 404 patients experiencing acute stroke, 39 (9.65%) were >90 years old (average age 91.73±2.34), and 82% were females. Four patients had cognitive impairment (Alzheimer disease) whose quality of life was average for their age. Major risk factors for stroke were AF (64%), hypertension (51%), and diabetes mellitus (7%). Smoking habits, before stroke or transient ischemic attack (TIA), had not …

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