Abstract
~ treptococcuspneumoniae causes local respiratory and serious systemic infections in children. Duri n g the past 10 years, an ever-increasing proportion of pneumococcal isolates has become resistant to penicillin and other antibiotics administered routinely to treat infections associated with this microorganism. Although physicians caring for children should be aware of this growing problem and select appropriate treatment strategies when managing pediatric infections that may be caused by these bacterial strains, the implications for treatment are not always clear-cut. This review examines several aspects of antibiotic resistance in S. pneumoniae, with an emphasis on how this resistance influences the approach to treating the wide variety of infections caused by this important pathogen.
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