Abstract
(14b R)-2-Methyl-1,2,3,4,10,14b-hexahydrodibenzo[ c, f]pyrazino[1,2- a]azepine, ( R)-(−)-mianserin 1a was synthesised in several steps in good enantiomeric purity with the use of ( S)-(−)-α-methylbenzylamine 5. The absolute configuration was assigned on the basis of X-ray data.
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