Abstract

Stereoselective synthesis of dihydropyrimidinone glycoconjugates in high yields, from different sugar aldehydes, by a three-component coupling (Biginelli) reaction is reported. In this new method, HC1 generated ‘in situ’ from2,4,6-trichloro[l,3,5]triazine(TCT; 10 mol%), was used under mild and solvent free reaction conditions.

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