Abstract
Background and Purpose
 Children with spastic cerebral palsy usually display elevation in muscle tone, a decline in gross motor functional abilities , feeding problems and sometimes it may accompanied by visual problems. Studies on stem cell treatment are in their early stages concerning their effect on cerebral palsy. 
 Methods 
 A child with spastic cerebral palsy on level v on gross motor function classification system was selected for autologous bone marrow derived mononuclear transplantation cell. Muscle tone, gross, fine motor abilities, feeding abilities and visual abilities were assessed on 4 occasions, prior the transplantation, immediately after the transplantation, after 6 months and after 1 year.
 Results No effect of stem cell transplantation was shown on the child.
 Conclusion Further research studies should be done on the subject but using different population rather than children on level V Gross motor function classification system
Highlights
Cerebral Palsy (CP) is a neurodevelopmental disorder caused by an injury to the immature cerebrum
The purpose of the current study was to evaluate the efficacy of stem cell transplantation for gross motor functions, fine motor functions, feeding, vision and spasticity in a child with cerebral palsy (CP)
Bone Marrow-derived Mononuclear Cells (BMMNCs) were extracted from the posterior superior iliac spine and infused intrathecally (L4-L5) and transplanted into a child with spastic CP
Summary
Cerebral Palsy (CP) is a neurodevelopmental disorder caused by an injury to the immature cerebrum. It leads to motor impairments which cause a reduction in muscle strength, cardiorespiratory function and motor functional activities [1]. Cerebral Visual Impairment (CVI), previously known as cortical visual impairment, is defined as a subnormal visual acuity - despite normal ocular examination - due to damage or injury to the posterior brain lobe or the posterior visual pathways [3]. Spasticity is a velocity dependent increase in the stretch reflex. It is a common disorder among children with CP which affects their whole body [5], leading to a reduction in their gross motor functions and activity participation [6]
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