Abstract

SOME YEARS AGO, A RECURRING skit on the late-night comedy show Mad TV featured the Coffee Guy an overcaffeinated Java fiend whose bulging eyes, hyperactivity and uncontrollable shaking didn't stop him from gulping down pots of the stimulant beverage whenever he had the chance. While many people might envy the Coffee Guy's ability to stay awake, they probably wouldn't trade their sanity for it. Amphetamine-like drugs, while much better than coffee at keeping people up and running, are even worse than caffeine in the side-effect department. Use too much, and you run the risk of addiction and psychosis. But although most sleep researchers would say the average workaholic should quit trying to subvert nature's sleep imperative with chemicals, there are situations when not sleeping is a good thing. The U.S.'s 125,000 narcoleptics, for whom staying awake during the day can be impossible, rely on drugs to let them live more normal lives. And the ...

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