Abstract
Rupture of coronary plaque probably accounts for half of perioperative myocardial infarctions. Because statins have plaque-stabilizing effects, they are plausible candidates for preventing perioperative MIs. In the industry-supported DECREASE-III trial, Dutch researchers randomized 497 statin-naive patients scheduled for elective vascular surgery (carotid, aortic, or lower extremity) to receive daily extended-release …
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