Abstract

Under the conditions of the pig-breeding complex, the state of cellular immunity in sows during the fetal period of gestation was studied. With the onset of gestation (days 38-40), the animals showed a decrease in non-specific cellular protection, as evidenced by a decrease in the number of circulating active phagocytes, their absorption activity on days 38-40 of gestation, the functional reserve of cells on days 38-40 and 78-81 and suppression of T-cell immunity, manifested by a significant increase in the content of T-lymphocytes-suppressors, a decrease in the number of T-helper cells and the immunoregulatory index. With an increase in the gestation period in animals, the activation of cellular and humoral immunity associated with the body response to the introduction of antiviral vaccines was recorded, that was manifested by an increase in the count of T- and B-lymphocytes, T-helper cells, a decrease in the number of T-lymphocytes-suppressors and an increase in the immunoregulatory index.

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