Abstract
Although specimen collection is acknowledged to be a critical factor in the testing of chlamydia, rarely do studies examine the effects of specimen transport on laboratory results. To compare the results on specimens shipped in a controlled environment with duplicate specimens exposed to environmental conditions such as heat or extended time in transit. Duplicate specimens were collected from 1,017 women tested at South Carolina public health clinics. One specimen from each woman was shipped by courier and the other by U.S. mail. The results, swab collected first, method of transport, and temperature during shipment were compared for each set of specimens. Specimens were tested with the Gen-Probe PACE 2 test. Mailed specimens were exposed to longer transport times and elevated temperatures; despite this, 99% of the results using courier specimens agreed with the mailed specimen results. Eighty-eight women tested positive and 891 women tested negative for chlamydia on both specimens. When the 11 specimens with discrepant results were retested by polymerase chain reaction, 10 were positive for chlamydia, with 9 concurring with the mailed specimen results. Results of specimens in this study were not adversely affected by heat and extended transit times when transported by U.S. Mail.
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