Abstract
In this study, the polydopamine (PDA) film was coated on polished 316Lss and then thermally treated at 150 °C (labeled as PDA-Th150), and the stability of coatings was also investigated. Straining test indicated that PDA-Th150 coating performed better in affording sufficient adherence to 316 L SS substrate. Moreover, both PDA and PDA-Th150 coating suffered slight swelling during immersion in deionized water (pH = 6.5). X-ray photoelectron spectroscopy results showed that during immersion, latent nucleophilic reaction via amines inside PDA coating occurred. This led to an enhanced cross-linking and thus gradually promoted the coating stability. Moreover, larger amount of bovine serum albumin (BSA) was immobilized onto PDA-Th150 coating and performed well in anti-platelet adhesion. A high retention of immobilized BSA was observed even after immersion for 30 days. These tests suggested that PDA was stable enough and performed well in surface functionalization, which might enrich the research and application of PDA.
Highlights
Surface properties are considered to be of significance and surface modification techniques are highlighted in current material design for obtaining desirable effects [1,2,3]
Catechols were oxidized to quinones and primary amino groups were somewhat consumed after thermal treatment
PDA-Th150 coating was less hydrophilic with a water contact angle (WCA) value of 86.4 compared with PDA coating (66.3)
Summary
Surface properties are considered to be of significance and surface modification techniques are highlighted in current material design for obtaining desirable effects [1,2,3]. In relation to biomedical research and applications, many efforts have been devoted to design engineer surface for desirable properties, including bioactive coatings, biomimetic construction and plasma treatment [4,5,6,7]. Series of biomolecules have been immobilized onto PDA surface and introduced desirable effects [15,16,17,18,19]. These results indicated that PDA was an effective way in surface functionalization
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