Abstract
Recent statistical evidence suggests that allergens are more stable and more highly expressed than other proteins from an allergen source. These factors may influence human exposure and, on a smaller scale, stability may affect processing by sentinel dendritic cells skewing the immune response toward allergy. Interestingly, for cockroach allergens purified from frass, the allergen stabilities were not statistically greater than their non-allergen counterparts, likely due to the high mean stability of the latter.
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