Abstract

The additive total small-vessel disease (SVD) burden score is associated with lacunar stroke and represents the effect. This result suggests that smoking and hypertension are preventable risk factors and that this burden score should be used in research and clinical practice to capture the overall consequences of SVD. See p. 1228 From editorialists Jickling & Chen: “As the scale is refined, the hope is that a comprehensive evaluation of cerebral SVD will improve our understanding and treatment of SVD, and ultimately improve brain health.” See p. 1224 Multifeature analysis was performed using MRI metrics obtained at 3T, focusing …

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