Abstract
Single-slab 3D DIR (double inversion recovery) and 3D FLAIR images of 56 matched fresh brain samples from 14 patients with chronic multiple sclerosis (MS) were acquired at 1.5 T. DIR is a useful technique to visualize cortical lesions in MS; many lesions are still missed, but those that are detected are likely actual lesions in terms of histopathology. See p. 302 From editorialists Ciccarelli & Chen: “Although DIR MRI is a recent innovation, it has provided important insights into the occurrence of cortical pathology in all subtypes of MS and the association …
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