Abstract

Two novel methods for inducing partial spontaneous resolution of conglomerates by crystallisation were proposed. The first one, termed ‘internal entrainment’, involves using a single crystal as the seed from a primary racemic mixture in its resolution by entrainment. The second method involves crystallisation under deficiency of a conglomerator, which causes homochiral packing of the crystals. Both methods were applied to Co(III) complexes with the effect of resolution up to 83% e.e.

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