Abstract
Diuretics is the group of drugs that are recommended as first-line therapy in patients with hypertension. This proved their efficiency both in moderate increase hypertension, and in a stable that can not be corrected by other groups of drugs. Spironolactone (veroshpiron) has been studied in large randomized placebo-controlled research aimed at studying the effect of the diuretic to lower SBP and DBP and distant positive effects in its application: prevention of fatal complications of cardiovascular disease. Proved that purpose veroshpiron in patients with resistant hypertension and heart failure, contributes to more effective blood pressure control than with other members of the group (eg, eplerenone). Spironolactone improves the condition of patients with heart failure: reduces clinical manifestations of angina and improves prognosis.
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