Abstract

ABSTRACT Objective: To evaluate the existence of a possible significant correlation between the quality of life of outpatients with osteoporosis and the Spinal Deformity Index (SDI), a radiographic method for semiquantitative assessment of the spine that enables the identification of prevalent and incident fractures. Methods: A cross-sectional observational study carried out with female patients, Caucasians, over 50 years of age, with a densitometric diagnosis of osteoporosis and in an outpatient follow-up, who were submitted to the Oswestry Disability Index (ODI) and SF-36 questionnaires to measure the direct and indirect damage of vertebral fragility fractures on quality of life. The scores obtained in these questionnaires were correlated with the SDI scores, calculated from the radiographs of the lumbar and thoracic spine. Results: 48 patients completed the study, with a mean age of 69.6±6.7 years, mean body mass index (BMI) of 25.4±3.4 kg/m2, mean ODI of 25.1±17.9%, mean SF- 36 of 428.7±192.4 and mean SDI of 4.3±3. For the statistical analysis, Spearman's coefficient was used (p ≤ 0.05). Conclusion: There is no statistically significant correlation between the SDI and the scores obtained on the ODI and SF-36 quality of life questionnaires. Level of evidence: III. Study of non-consecutive patients, without gold standard, applied uniformly.

Highlights

  • Osteoporosis is a global public health problem that affects large portions of the population, especially in connection with population aging

  • A cross-sectional observational study carried out with female patients, Caucasians, over 50 years of age, with a densitometric diagnosis of osteoporosis and in an outpatient follow-up, who were submitted to the Oswestry Disability Index (ODI) and SF-36 questionnaires to measure the direct and indirect damage of vertebral fragility fractures on quality of life

  • The exclusion criteria were: male patients or patients under 50 years of age or non-Caucasians; patients submitted to some previous surgical procedure to the spine; patients with congenital deformities of the spine; patients who did not agree to collaborate with research by not signing the Informed Consent Form (ICF)

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Summary

Introduction

Osteoporosis is a global public health problem that affects large portions of the population, especially in connection with population aging. It is a systemic multifactorial osteometabolic disease characterized by decreased bone mineral density (BMD) and changes in bone microarchitecture, with a consequent increase in fragility and susceptibility to fractures.[1] Vertebral fractures represent almost half of all osteoporotic fractures and are at least twice as frequent as hip fractures.[2] In Brazil, in the population over 65 years of age, the prevalence of these fractures due to fragility is as high as 27.5% among women and 31.8% among men.[3] given that many vertebral fractures are asymptomatic, the problem is more severe than these figures indicate.[1,4]. Fractures of the vertebral bodies are one of the main characteristics of osteoporosis.[5,6] The presence of one vertebral fracture leads to a five-fold risk of another vertebral fracture and a two-fold risk of a non-vertebral fracture. Vertebral fractures have greater capacity than BMD or bone remodeling markers to predict the risk of subsequent fractures

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