Abstract
The effect of oxytocin on sperm output of rabbits was studied in animals injected twice daily for 22 days with 1 IU per kg body weight of synthetic oxytocin and comparing them with saline injected rabbits. Beginning 3-4 weeks after the start of oxytocin injections a significant increase in sperm output was noted (p less than .001). After about 7 weeks a decrease in sperm output was noted (p less than .05). Histologic examination of the testes 18 days after the start of injections showed an increase in type B spermatogonia primary spermatocytes and spermatido (p less than .001). Geitoli cells decreased (p less than .05) in number and the diameter of seminiferous tubules increased slightly (p less than .01). Evidence showed that oxytocin was more potent in individual animals with a subnormal testicular function.
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