Species composition of certain strains of microorganisms in the development of upper respiratory tract disease in agricultural workers

Abstract

Introduction. Microbiocenosis is a self-regulating system of relationships between the body and microflora. Ensuring the technological process of agricultural production involves contact with conditionally pathogenic and pathogenic microflora. The spread of antibacterial drug resistance is a matter of concern. Materials and methods. There was studied the microbiocenosis of the upper respiratory tract in agricultural enterprises: in the absence of inflammatory diseases; the clinical picture of diseases of the ENT organs, and the susceptibility of the isolated strains to antibacterial drugs. Results. Working conditions of employees correspond to classes 3.1 - 3.3. Typical representatives are strains of Streptococcus, Staphylococcus, Micrococcus, Neisseria, Corynebacterium. The etiological share of S. Aureus, C. Albicans, E. Coli, Kl. Pneumoniae, Ps. Aeruginosa, predominates in the formation of inflammatory diseases. Staphylococcus are most susceptible to Cefotaxime and Sparfloxacin, followed by Cefepime, Levofloxacin and Amikacin. Strains of Kl. pneumoniae are susceptible to Cefotaxime and Sparfloxacin; strains of Pseudomonas aeruginosa - to Cefepime and Ceftazidim; C. Albicans and C. crusei - to Amphotericin B and Fluconazole. Conclusion. The complex industrial factors of agricultural production contributes to the violation of the ratio of microbial associations even against the background of clinical health, which is a risk factor for the development of inflammatory processes. S. Aureus strains; Candida Albicans; Klebsiella Pneumoniae play the leading role. Pseudomonas aeruginosa and E. Coli. The isolates demonstrate multidrug resistance to antimicrobial drugs.