Abstract
The development of decidual cells in the endometrial connective tissue of the pregnant mouse during the implantation of ova was studied with the electron microscope. During differentiation contacts of three types were formed between neighboring decidual cells. Some contacts were unspecialized while others were tight junctions similar to those found between liver and heart muscle cells. In later stages there were complex knob-like contact regions with tight junctions. Tight junctions, in which the outer lamellae of the adjacent plasma membranes are closely apposed, as in the zona occludens of epithelia, appear to be rare in adult connective tissue, and their possible significance in implantation is discussed.
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