Sovereign Cloud Buildout Using Repeatable and Scalable Patterns

This study utilizes bibliometric analysis to review the academic literature systematically focused on the influence of digital transformation and digitalization on business and innovation research. A total of 700 articles in Scopus related to the research topic were analyzed. Trend analysis of digital transformation and digitalization, using Google Books Ngram Viewer and Google Trends, indicated the increasing curiosity in this theme in English books and search engines. The analysis of the dynamic of publications in Scopus showed a ten-time increase in research focusing on business, innovation and digital transformation. The performance analysis indicated the top 10 countries with the highest contribution to the research topic. The study then employed citation analysis to identify the most influential publications on the research topic in 2018-2023. Using the VOSviewer, the co-occurrence analysis identified the main thematic clusters of keywords and the evolution of the research themes over the past six years.

Colombian law recognizes that traditional Indigenous and Black authorities can exercise legal jurisdiction and apply their laws and traditions in their ancestral territories. Despite this legal recognition, the legal system does not operate in a way that genuinely guarantees legal pluralism. In practice, higher courts repeatedly overturn or dismiss decisions by indigenous legal authorities.
 As a result of the 2016 Peace Agreement between the Colombian Government and the former guerilla of the Revolutionary Armed Forces of Colombia – The People’s Army (“FARC-EP” in Spanish), a transitional justice tribunal was established: the Special Jurisdiction for Peace (“SJP” or “the Special Jurisdiction”). The Special Jurisdiction’s main task is to investigate and try the most serious crimes committed during the armed conflict, a conflict that has disproportionately impacted racialized communities. The SJP, unlike other tribunals in Colombia, has sought to adapt its work to meet the reality of legal pluralism by: 1) negotiating protocols for inter-jurisdictional interaction between the SJP and ethnic authorities, 2) consulting with Indigenous and Black communities on the adoption of some legal instruments, and 3) having a dialogue between equals with ethnic authorities when potential jurisdictional conflicts arise. This paper seeks to analyze this interaction and how it has allowed the Special Jurisdiction, as transitional justice mechanism, to work in close cooperation with Indigenous and Black communities in Colombia. As will be discussed throughout this paper, through the lens of the legal pluralism framework, such interaction has strengthened the legitimacy and recognition of Indigenous and Black communities’ legal authorities as parallel legal orders that can operate side-by-side with the State judicial system. This, in turn, has created an important precedent that can be emulated by other court jurisdictions in Colombia and elsewhere.

In recent years, the relationship between digital transformation and innovation became very popular topics, attracting extensive attention, and inspiring a number of documents. Although much literature discusses the intersection of both fields, most works offer neither a complete nor a truly objective overview of the current state of research. Therefore, there is a need for a comprehensive and objective review of research themes to analyze the intersection. For this purpose, based on the literature collected from the Web of Science (WoS) database published between 1994 and 2021, co-word analysis was carried out to explore research themes and identify the most salient themes in digital transformation and innovation research. The results of scientific output show that digital transformation and innovation is attracting increasing academic interest of scholars from many countries and different fields. The distribution of high-frequency keywords shows that the research in this field is multidisciplinary, including not only many economic and management fields, but also many classical theories and research methods. The clustering results of keywords reveal five clusters of themes: diffusion and adoption of technology and innovation, digital innovation management, digital transformation management, digital platform and ecosystem, and digital entrepreneurship and economy. According to the results of strategic diagram and performance analysis, digital innovation management and digital transformation management are the mainstream of research, while digital platform and ecosystem and digital entrepreneurship and economy have strong development potential. This study provides a snapshot of the thematic development of digital transformation and innovation research, enabling researchers to better master the current situation and suggesting the development trend in the future.

e13609 Background: Oncology is renowned for leading innovation in research and in care. However, digital innovation in cancer care and research appears to be limited relative to other therapeutic areas. Methods: A multi-stakeholder roundtable, co-hosted by the Digital Medicine Society (DiMe) and Moffitt Cancer Center, convened experts from 35 leading organizations in life science R&D, regulators, payers, innovators, and with core representation from cancer patients and patient experts. Discussions addressed the current state of digital innovation in cancer care, root causes of digital health innovation challenges in oncology, and identifying action-oriented approaches to collaborative solutions needed to advance the safe, effective, ethical, and equitable use of digital innovations in oncology. Results: There was consensus among roundtable attendees that digital innovation lags behind in oncology relative to other therapeutic areas. Challenges identified as ‘low hanging fruit’ for digital innovation include reducing patient administrative burden, supporting care navigation, optimizing decision making in care and research, optimizing clinical pathways, and improving how we monitor both performance status and safety. Reducing financial toxicity and disparities in disease burden must be imperatives of digital innovation in oncology. Access to care and health outcomes for all patients must also be improved. Impediments to digital innovation in oncology include a proliferation of digital point solutions as opposed to system level innovations; transactional digital solutions that do not promote ongoing engagement and reengagement for the lifetime of the patient journey; lack of trust among patients and clinicians; the absence of data sharing incentives and infrastructure; and business and payer disincentives to digital transformation. Conclusions: Digital innovation frameworks can support more effective and equitable approaches to care that are accessible, scalable, and inclusive, thereby reducing the burden of cancer. To achieve this, clinical, technical, and operational best practices necessary to develop, design, and deploy high-quality digital interventions into cancer care must be established. There is no reason for the successful adoption of digital interventions in oncology to lag behind other therapeutic areas. Intentional action with urgency is required by the multi-stakeholder community through a collaborative effort to realize the full promise of digital innovation for patients and the systems that support those who care for them.

ObjectiveDigital ecosystems integrate interconnected tools, platforms, and stakeholders to support healthcare delivery. While prior research has examined their technological architecture, limited attention has been paid to their role in enhancing communication and collaboration, particularly in low-resource settings. This scoping review explores how digital ecosystems facilitate these functions, identifying key components, applications, barriers, and enablers.MethodsFollowing the Arksey and O’Malley framework, enhanced by Levac et al., a scoping review was conducted using Scopus, PubMed, JSTOR, and Emerald. The review included studies published between 2009 and 2024 and adhered to PRISMA-ScR reporting standards. A total of 15 eligible studies were analysed thematically.ResultsFive core ecosystem components emerged: interoperability, stakeholder diversity, patient-centred tools, innovative platforms, and knowledge sharing. Ecosystems supported real-time communication, improved service coordination, and enhanced care accessibility through tools such as telemedicine and mHealth. In low-resource settings, barriers included fragmented digital infrastructure, privacy regulations, and provider resistance. Enablers included strong stakeholder engagement, supportive policies, and low-bandwidth digital solutions like SMS-based platforms.ConclusionThis review highlights the communicative and collaborative functions of digital ecosystems as central to their value in healthcare not just their technological capacity. It contributes a contextual perspective by detailing implementation challenges and adaptations in low- and middle-income countries. To advance the field, future research should adopt standardized frameworks, expand empirical studies in underrepresented settings, and emphasize inclusive, scalable designs that respond to local healthcare realities.

We analyze the role of co-inventor collaboration with China and the USA on a country’s increase in centrality in global knowledge networks. Building on research in economic development, innovation, social networks, and institutional theory, we find that co-patenting with Chinese inventors is positively related to a country’s centrality in global knowledge networks and that this relationships is negatively moderated by collaboration with the current most central knowledge network, namely that of the USA. We also find a negative effect from intellectual property rights protection and high transparency on the relationship between a country’s centrality when collaborating with China. Regression analyses of a panel of 197 countries for the years 2002-2015 support these findings, which contribute to recent debates on knowledge networks and international cooperation. In terms of theory, we extend social networks approach on international business literature, focusing on what institutional characteristics are related to participation in knowledge networks. Regarding policy makers, our findings can be used to encourage international collaboration for increased access to new sources of knowledge that fosters innovation while keeping a close eye on local institutions.

With 80% of wastewater globally discharged untreated and non-renewable energy resources rapidly depleting, the call for sustainable solutions has never been louder. Nature-Based Technologies for Wastewater Treatment and Bioenergy Production explores the groundbreaking integration of natural systems and advanced technologies to address critical global challenges in wastewater management and renewable energy. This book delves into nature-based technological approaches such as constructed wetlands, bio-aided filtration systems, and photobioreactors for microalgae cultivation, showcasing their potential to transform wastewater into a valuable resource while significantly reducing the environmental footprint. Rooted in innovative research, the book emphasizes advanced techniques for nutrient recovery, pollutant removal, and carbon capture. It examines the role of emerging technologies, such as high-rate algal ponds and hybrid treatment systems, in achieving cost-effective and energy-efficient wastewater treatment. Highlighting the science behind microalgae-based biodiesel production, the book also explores the potential of algae-derived bioproducts such as biofertilizers, bioplastics, and animal feed supplements, underscoring the role of these innovations in building a sustainable bioeconomy. Rich in real-world applications, this reference work provides practical insights for academia, researchers, students, industry professionals, scholars, practitioners, and policymakers. It addresses critical issues such as wastewater management, rising energy demands, and carbon footprint while demonstrating scalable solutions for global implementation. Nature-Based Technologies for Wastewater Treatment and Bioenergy Production envisions a future where nature-inspired technologies lead to a thriving circular bioeconomy. By combining natural processes with advanced technologies, this book lays the roadmap for transforming environmental challenges into sustainable opportunities and fostering cleaner and more resilient planetary health. ISBN: 9781789064094 (paperback) ISBN: 9781789064100 (eBook) ISBN: 9781789064117 (ePub)

<p>The shaft at Reiche Zeche mine provides direct access to the research and training underground mine of the reputed TU Bergakademie Freiberg, where advanced scientific research and practical education is executed for more than 100 years now.</p><p>Since 1919, the former ore mine is used for educating and training of miners, engineers and mine surveyors by the TU Bergakademie Freiberg. Drifts and tunnels of the mine stretch over several kilometres at depths down to 230 m. Today, the Reiche Zeche mine plays a major role in mining research and related activities including various research institutes and industrial partners. Several underground test facilities and laboratories are in use and play a key role in university education. A variety of local (15 institutes of TU Bergakademie Freiberg) and external partners (30 from 26 countries) are actively shaping research and education in the mine.</p><p>Real-world applications and cutting-edge technologies are tested in a stimulating environment underground, helping to improve competitiveness, leadership, creativity and critical thinking of researchers, companies and stakeholders.</p><p>Most recent research projects provide innovative solutions in way different fields. Robotics, smart mining, geophysical monitoring, a blasting chamber used for material science research, and also new mining technologies such as biohydrometallurgical mining for the winning of metals from ores, tailings and recycling material are only a small sample of the Reiche Zeche´s advanced innovation areas.</p><p>At Reiche Zeche mine, an efficient research and innovation environment is provided. It includes high quality underground spaces, cutting-edge methodology, state-of-the art labs, high-quality staff, resources and services to industries, talented individuals, leading researchers and teams from six continents, who truly want to make a real positive difference in the Society, contributing therefore, to sustainable optimisation for the raw materials value chain.</p><p>We are actively contributing to the European Underground Laboratories (EUL) network, forming an efficient platform for future, innovative research and business activities in underground laboratories. We are always open for collaboration with interested researchers and related stakeholders.</p>

Bioactive compounds are natural or synthetic substances with regulatory roles in metabolic processes. Brazil, known for its rich biodiversity and strong expertise in organic chemistry, holds great potential for discovering bioactive molecules. However, the vast amount of data generated in this field is often scattered and difficult to access. The IRACEMA (Innovative Research, Analysis, and Computational Exploration of Molecules Assembled in Brazil) project addresses this challenge by establishing the first comprehensive database of synthetic bioactive compounds in Brazil. This platform integrates biological activity data, manually curated from the literature, with cheminformatics-based predictions of physicochemical and ADME properties to facilitate the exploration of structure-activity relationships (SARs) by end users. The project's technical architecture employs modern web technologies for both frontend (React) and backend (NestJS/Node.js and Python/Flask microservices) development. The system delivers an interactive platform for molecular visualization and analysis, with PostgreSQL and Prisma ensuring robust data management. By democratizing access to data, IRACEMA (available at https://iracema.fcf.usp.br/) strengthens Brazil's position in bioactive compound research, bridging the gap between academic discoveries and real-world applications.

Integrating new technologies into long-term care (LTC) presents exciting opportunities and significant challenges. As the aging population grows, there is increasing interest in how artificial intelligence (AI)-enabled robots can support residents’ well-being and improve care delivery. Drawing on my research with AI-powered social robots such as Aether, Paro, and Lovot, this presentation examines the practical considerations of adopting these innovations in LTC. Robotic technologies offer many benefits, including enhanced engagement, cognitive stimulation, companionship, and reduced loneliness. These tools may also help alleviate caregiver burden by assisting with repetitive tasks or providing entertainment and therapeutic interactions. However, implementation presents challenges. Ethical concerns—such as ensuring equitable access, avoiding substitution of essential human care, and preserving dignity and autonomy—must be carefully navigated. Practical barriers, including staff training, infrastructure adjustments, cost, and acceptance by residents and care providers, also affect successful adoption. This presentation highlights key lessons learned and offers strategies for conducting successful innovation research. Early-career scholars should seek diverse funding sources, secure pilot study grants, and align projects with practice needs. Networking within aging, technology, and healthcare communities fosters mentorship, partnerships, and knowledge exchange. Publishing in both academic and practitioner-oriented outlets bridges research and real-world application. By ensuring responsible implementation, AI-enabled robots can be used ethically and effectively to support resident well-being, promote person-centered care, and complement rather than replace human interactions in LTC settings.

In recent years, innovative research has been widely conducted on flexible devices for wearable electronics applications. Many examples of wearable electronics, such as smartwatches and glasses, are already available to consumers. However, strictly speaking, the sensors used in these devices are not flexible. Many studies are underway to address a wider range of wearable electronics and the development of related fields is progressing very rapidly. In particular, there is intense interest in the research field of flexible pressure sensors because they can collect and use information regarding a wide variety of sources. Through the combination of novel materials and fabrication methods, human-machine interfaces, biomedical sensors, and motion detection techniques, it is now possible to produce sensors with a superior level of performance to meet the demands of wearable electronics. In addition, more compact and human-friendly sensors have been invented in recent years, as biodegradable and self-powered sensor systems have been studied. In this review, a comprehensive description of flexible pressure sensors will be covered, and design strategies that meet the needs for applications in wearable electronics will be presented. Moreover, we will cover several fabrication methods to implement these technologies and the corresponding real-world applications.

Advanced Materials Technologies was launched in April 2016 with the aim to report on research that bridges the gap between materials science and real-world applications. Now, we celebrate an important and exciting milestone for Advanced Materials Technologies: With the recent release of the 2018 Clarivate Journal Citation Reports the journal has received its first (partial) Impact Factor of 4.6! The top cited articles published in 2016 are shown in Table 1. “We're off to a strong, aggressive start, fueled by high quality papers from the leading figures in the field! Advanced Materials Technologies is already living up to its aim of publishing first-class, innovative research with a practical bent and a potential for broad engineering significance.” – Prof. John Rogers, Co-Chair of the International Editorial Advisory Board As of today, over 850 manuscripts have been received (and the number is increasing!) and well over 350 articles have been published in 29 issues. Topics that have proved popular so far this year include 3D printed organ models and microfluidic devices, paper-based nanocomposites, and pressure sensors for electronic skin. For the Editors' selection of some of the most outstanding Advanced Materials Technologies articles published in 2017, continue reading here: Many thanks to outgoing board members J. J. Baumberg and Jiang Chang for their support during the crucial launch phase of the journal. We are looking forward to new, exciting content at Advanced Materials Technologies! Please submit your manuscript today and stay tuned to the newest content at www.advmattechnol.com. P.S. We would be happy to receive your feedback anytime at [email protected]

This journal aims to promote, publish and promulgate high-quality, innovative research. As laudable as this is, it is not enough. Unless this research culminates in practical and cost-effective interventions capable...

Dissolving microneedles in transdermal drug delivery: A critical analysis of limitations and translation challenges.

This study examines undergraduate science students perceive the impact of Information and Communication Technology (ICT) on improving science education. It focuses on three key aspects: curriculum design and development, the teaching and learning process, and research innovation and extension activities. The study explores the integration and impact of ICT on these educational aspects. A descriptive survey design was employed, collecting data from 40 B.Sc. students at Jamia Millia Islamia through a structured questionnaire. The findings reveal that while ICT is widely recognized for its potential to enhance content delivery and align with learning objectives, there are areas, such as personalized learning and the use of digital labs, where its integration remains inconsistent. The study also highlights the importance of ICT in fostering transparency, equity, and collaborative learning. However, the varying levels of student engagement indicate a need for improved access, awareness, and training to fully optimize ICT's benefits in science education in connecting theoretical knowledge with real-world applications. The findings have implications for teachers, policymakers, and researchers seeking to use the potential of ICT in science education.