Abstract
A description of apparatus designed for the routine large-scale assay of antibiotics employing as a basis linear diffusion in glass capillary tubes is presented. The apparatus described includes the glass capillaries, a device for filling large numbers of them simultaneously with seeded agar, a zone reader for the semiautomatic reading of zone lengths, and an assembly suitable for the rapid cleansing of capillary tubes, test tubes, and bottles. The capillaries used were treated with a water-repellent coating such as ferric stearate which caused the agar column to bond more tightly to the glass.
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