Abstract
Several trials for the COVID-19 pandemic are found. Prof. Shunji Nakamura, Tokushima University was awarded the 2014 Nobel prize in Physics for light-emitting diodes (LEDs). Deep ultraviolet LED (DUV-LED) causes SARS-CoV-2 inactivation as 99.9% by 265 nm. Gc protein-derived macrophage-activating factor (GcMAF)-based immunotherapy has a wider application for serious infection, chronic fatigue syndrome, and cancers. Covid center in Naples submitted a phase II report concerning GcMAF and COVID-19 in Feb 2021. 5-aminolevulinic acid (5-ALA) and its metabolite protoporphyrin IX (PpIX) show anti-inflammatory and antiviral effects for Zika, Dengue, influenza A viruses, and SARS-CoV-2. These results hopefully contribute to the research development for COVID-19.
Highlights
Story of the Invention of Efficient InGaN Blue-Light-Emitting Diodes (Nobel Lecture)
He was awarded the 2014 Nobel prize in Physics [5]. Using this deep ultraviolet light-emitting diode (DUV-Light Emitting Diode (LED)), quantitative evaluation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inactivation was reported as 99.9% in 2021 [6]
Gc protein-derived macrophage-activating factor (GcMAF) has the possibility of the role for suppressing the severity of COVID-19-induced immune responses [10]
Summary
Story of the Invention of Efficient InGaN Blue-Light-Emitting Diodes (Nobel Lecture). Keywords Light Emitting Diode, Deep Ultraviolet Light Emitting Diode, Gc protein-derived Macrophage-Activating Factor, 5-Aminolevulinic Acid, Protoporphyrin IX, Severe Acute Respiratory Syndrome Coronavirus-2 Macrophage-Activating Factor; 5-ALA: 5-Aminolevulinic Acid; PPIX: Protoporphyrin IX; SARS-Cov-2: Severe Acute Respiratory Syndrome Coronavirus-2 Using this deep ultraviolet light-emitting diode (DUV-LED), quantitative evaluation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inactivation was reported as 99.9% in 2021 [6].
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