Abstract

1. Rat phrenic nerve preparations were used in vitro to study action potential amplitude and nerve conduction time under varying conditions of Pco(2) and sodium bicarbonate concentration in the surrounding Krebs solution.2. A correlation was found between action potential amplitude and pH but not between action potential amplitude and Pco(2).3. A better correlation was found between conduction time and pH than between conduction time and Pco(2).

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