Solvothermally grown ZnO/BiOCl photocatalyst for solar-light-responsive degradation of tetracycline antibiotic

Carbon-based heterostructure from multi-photo-active nanobuilding blocks SrTiO3@NiFe2O4@Fe0@Ni0@CNTs with derived nanoreaction metallic clusters for enhanced solar light-driven photodegradation of harmful antibiotics

Degradation of tetracycline antibiotics by Fe2+-catalyzed percarbonate oxidation

Bifunctional Pt-loaded steel slag matrix composites for the detection and degradation of tetracycline antibiotics

A novel double anion layered photocatalyst Pb4(BO3)2SO4 with enhanced photocatalytic performance for antibiotic degradation

Simple synthesis of 2D/3D mpg-C3N4/ZnO nanocages with built-in driven Z-scheme heterostructures: Photocatalytic degradation of tetracycline antibiotics and lifting the limitation of the complex water environment

Synthesis and application of CdS nanorods for LED-based photocatalytic degradation of tetracycline antibiotic

Anchoring Bi4O5I2 and CDs on brown TiO2−x: S-scheme heterojunction mechanism for impressive degradation of several antibiotics under visible light

Tetracyclines are one class of widely used antibiotics. Meanwhile, due to abuse and improper disposal, they are often detected in wastewater, which causes a series of environmental problems and poses a threat to human health and safety. As an efficient and environmentally friendly method, enzymatic catalysis has attracted much attention. In previous studies, we have designed an efficient peroxidase (F43Y/P88W/F138W Mb, termed YWW Mb) based on the protein scaffold of myoglobin (Mb), an O2 carrier, by modifying the heme active center and introducing two Trp residues. In this study, we further applied it to degrade the tetracycline antibiotics. Both UV-Vis and HPLC studies showed that the triple mutant YWW Mb was able to catalyze the degradation of tetracycline, oxytetracycline, doxycycline, and chlortetracycline effectively, with a degradation rate of ~100%, ~98%, ~94%, and ~90%, respectively, within 5 min by using H2O2 as an oxidant. These activities are much higher than those of wild-type Mb and other heme enzymes such as manganese peroxidase. As further analyzed by UPLC-ESI-MS, we identified multiple degradation products and thus proposed possible degradation mechanisms. In addition, the toxicity of the products was analyzed by using in vitro antibacterial experiments of E. coli. Therefore, this study indicates that the engineered heme enzyme has potential applications for environmental remediation by degradation of tetracycline antibiotics.

A novel functionalized nitrogen- and sulfur-co-doped nanocarbon dots for the fluorescence detection and photocatalysis degradation of tetracycline antibiotics.

Insight into the effects of hydroxyl groups on the rates and pathways of tetracycline antibiotics degradation in the carbon black activated peroxydisulfate oxidation process

A nonradical oxidation process initiated by Ti-peroxo complex showed high specificity toward the degradation of tetracycline antibiotics

The abuse of tetracycline antibiotics (TCs) has caused serious environmental pollution and risks to public health. Degradation of TCs by cold atmospheric plasmas (CAPs) is a high efficiency, low energy consumption and environmentally friendly method. In this study, a reactive molecular dynamics (MD) simulation is applied to study the interactions of reactive oxygen species (ROS) produced in CAPs and TCs (including tetracycline (TC), oxytetracycline (OTC), chlortetracycline (CTC) and demeclocycline (DMC)). As revealed by the simulation data at the atomic level, the main reaction sites on TCs are the acylamino, the dimethylamine, the methyl group, the site on the benzene ring and the tertiary alcohol. The interaction between ROS and TCs is usually initiated by H-abstraction, followed by the breaking and formation of the crucial chemical bonds, such as the breaking of C-C bonds, C-N bonds and C-O bonds and the formation of C=C bonds and C=O bonds. Due to the different structures of TCs, when the ROS impact OTC, CTC and DMC, some specific reactions are observed, including carbonylation at the site, dechlorination at the site and carbonylation at the site, respectively. Some degradation products obtained from the simulation data have been observed in the experimental measurements. In addition, the dose effects of CAP on TCs by adjusting the number of ROS in the simulation box are also investigated and are consistent with experimental observation. This study explains in detail the interaction mechanisms of degradation of TCs treated by CAPs with the final products after degradation, provides theoretical support for the experimental observation, then suggests optimization to further improve the efficiency of degradation of TCs by CAPs in applications.

Emerging pollutants such as tetracycline antibiotics (TCs) have garnered attention due to their ecological impacts and the evolution of drug resistance. However, the comprehensive monitoring of TCs remains inadequate. This study presents a multifunctional integrated system that addresses the limitations in current TCs research by combining detection, degradation, and bioimaging capabilities within a platform. By employing magnetic MgFe2O4 nanospheres, we achieve full-chain coverage for pollutant treatment, transcending the limitations of traditional single-function materials. To achieve this, we utilize machine-learning-driven precise detection technology and apply the graph neural networks model to analyze fluorescence spectra, successfully distinguishing between four TCs with highly similar structures. Subsequent dual-channel in vivo fluorescence imaging monitoring in zebrafish enables visualization of the spatial distribution of TCs types within living organisms and quantitative monitoring of TCs at different concentrations, providing a new tool for the in situ tracking of drug metabolism processes and ecotoxicological research. Lastly, the magnetic MgFe2O4 nanospheres exhibit efficient degradation capabilities, with degradation efficiencies exceeding 93.98% for all four TCs within 50 min. Additionally, the magnetic properties of the nanospheres address the challenge of nanomaterial recovery, enabling recycling of the catalyst. This work provides an innovative AI-material hybrid platform for intelligent pollution control.

Facile fabrication of melamine sponge@covalent organic framework composite for enhanced degradation of tetracycline under visible light

“Two-in-one” sulfur and nitrogen co-doped fluorescent silicon nanoparticles: Simultaneous as the fluorescent probe and photocatalyst for in-situ real time visual monitoring and degradation of tetracycline antibiotics