Abstract
Solitary metastasis of uveal melanoma to bone is extremely rare and usually associated with other organ involvement. We present a rare case of an ocular melanoma patient presenting with solitary metastasis to the clavicle two years after enucleation, without any other organ involvement. In this report, we tried to present our treatment strategy for the solitary metastasis of bone.
Highlights
Malignant melanoma accounts for 1–3% of all malignancies with an increasing incidence being seen worldwide [1, 2]
We present a rare case of an ocular melanoma patient presenting with solitary metastasis to the clavicle two years a er enucleation, without any other organ involvement
Over a 25-year period from 1973 to 1997, incidence of Uveal melanoma (UM) in the United State has been determined to be 4.3 cases per million people per year, which is similar to the report from European countries [16, 17]. ough UM is relatively rare compared with other malignant tumors, it contributes to a large proportion of deaths and leads to distant metastases, even a er successful treatment of the local tumor [18, 19]
Summary
Malignant melanoma accounts for 1–3% of all malignancies with an increasing incidence being seen worldwide [1, 2]. Uveal melanoma (UM) arises from melanocytes located in the choroid layer between the sclera and the retina. It is the most common primary malignant primary tumor of the eye, there are only about 1,500 diagnoses per year in the United States [3, 4]. Solitary metastasis of uveal melanoma to bone is extremely rare and usually associated with another organ involvement predominantly liver or lung [14, 15]. We present a rare case of an ocular melanoma patient presenting with solitary metastasis to the clavicle two years a er enucleation, without any other organ involvement
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