Abstract
In this article, a nanosuspension of AmB was prepared and mixed with the preformed parenteral emulsion Lipofundin® and subjected to high-pressure homogenization (SolEmuls® technology). Characterization was performed by photon correlation spectroscopy (PCS), laser diffractometry (LD), and zeta potential measurements. Drug incorporation was studied by using light microscopy. The produced emulsions were further investigated by comparing them with the commercially available Fungizone® in regard to antifungal efficiency and toxicity. Results suggest that through the SolEmuls® process the AmB forms a reservoir, out of which it is released in such a manner that it is more efficient and less toxic than Fungizone®.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
