Abstract

Whilst some populations have recently experienced dramatic declines in malaria, the majority of those most at risk of Plasmodium falciparum malaria still lack access to effective treatment with artemisinin combination therapy (ACT) and others are already facing parasites resistant to artemisinins.In this context, there is a crucial need to improve both access to and targeting of ACT through greater availability of good quality ACT and parasitological diagnosis. This is an issue of increasing urgency notably in the private commercial sector, which, in many countries, plays an important role in the provision of malaria treatment. The Affordable Medicines Facility for malaria (AMFm) is a recent initiative that aims to increase the provision of affordable ACT in public, private and NGO sectors through a manufacturer-level subsidy. However, to date, there is little documented experience in the programmatic implementation of subsidized ACT in the private sector. Cambodia is in the unique position of having more than 10 years of experience not only in implementing subsidized ACT, but also rapid diagnostic tests (RDT) as part of a nationwide social marketing programme. The programme includes behaviour change communication and the training of private providers as well as the sale and distribution of Malarine, the recommended ACT, and Malacheck, the RDT. This paper describes and evaluates this experience by drawing on the results of household and provider surveys conducted since the start of the programme.The available evidence suggests that providers' and consumers' awareness of Malarine increased rapidly, but that of Malacheck much less so. In addition, improvements in ACT and RDT availability and uptake were relatively slow, particularly in more remote areas.The lack of standardization in the survey methods and the gaps in the data highlight the importance of establishing a clear system for monitoring and evaluation for similar initiatives. Despite these limitations, a number of important lessons can still be learnt. These include the importance of a comprehensive communications strategy and of a sustained and reliable supply of products, with attention to the geographical reach of both. Other important challenges relate to the difficulty in incentivising providers and consumers not only to choose the recommended drug, but to precede this with a confirmatory blood test and ensure that providers adhere to the test results and patients to the treatment regime. In Cambodia, this is particularly complicated due to problems inherent to the drug itself and the emergence of artemisinin resistance.

Highlights

  • The importance of the private sector in the provision of malaria treatment is widely recognized [1,2,3,4,5,6,7,8,9,10]

  • Cambodia is in the unique position of having had a nationwide social marketing programme for both rapid diagnostic tests (RDT) and artemisinin combination therapy (ACT) in the private sector since 2002

  • These suggest that a subsidy on ACT can rapidly increase ACT availability in private outlets, decrease ACT consumer prices, increase ACT uptake and decrease artemisinin monotherapy use, these effects may tend to benefit relatively accessible populations rather than the more remote and poorer communities

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Summary

Introduction

The importance of the private sector in the provision of malaria treatment is widely recognized [1,2,3,4,5,6,7,8,9,10]. It is only recently that its potential role in increasing community access to good quality malaria treatment, through artemisinin combination therapy (ACT) and potentially parasitological diagnosis has been considered. The AMFm aims to increase access to ACT by lowering the cost of the drugs through a manufacturer-level subsidy. Public, private and not-for-profit first-line buyers will be able to purchase nationally-recommended ACT from manufacturers at around US$0.05 per dose, a fraction of their actual cost. It is anticipated that the saving will pass through the distribution chain, so that consumers will be able to purchase ACT at a price comparable to that of older less effective monotherapies (i.e. approximately $0.20 for an adult course) [11]. There has been a number of pilot studies [12,13,14], there is little documentation on subsidizing ACT at a programmatic level on which to base this roll-out [13,14,15]

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