Abstract
Background and Aims : Cholesteryl ester transfer protein (CETP) is known to reduce high-density lipoprotein cholesterol (HDL-C) levels and, as a result, increase cardiovascular risk. Serum levels of CETP are genetically determined, therefore the polymorphisms influencing it are also suspected to influence cardiovascular risk. This study aims to explore the association between 5 single nucleotide polymorphisms (SNPs) and their haplotypes (H) in CETP genes and the 10-year cardiovascular risk estimated by the Framingham Risk Score for hard coronary heart disease (FRSCHD) and for cardiovascular disease in general (FRSCVD), and the Systematic Coronary Risk Evaluation (SCORE) among the Hungarian general (HG) and Roma populations.
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