Abstract

Non-coding RNAs comprise the majority of the transcriptome and represent an emerging area of research. Among them, small nucleolar RNAs (snoRNAs) have emerged as a promising target as they have been associated with the development and evolution of several diseases, including psychiatric disorders. SnoRNAs are expressed in the brain, with some showing brain specific expression that indicate specific roles in brain development, function, and dysfunction. However, the understanding of the role of snoRNAs in conditions affecting the brain need further investigation to be better understood. This scoping review summarizes existing literature on studies investigating snoRNAs in psychiatry and offers insight into potential pathophysiological mechanisms to be further investigated in future research.

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